It seems that the herb "feverfew" (Tanacetum parthenium) is a pretty potent anti-migraine supplement, with most reviews/stories I have read saying that it works well, even in some chronic cases of migraines which have not responded to painkillers.
According to studies, it seems that it has anti-serotonin, anti-prostaglandin, anti-inflammatory effects:
"Feverfew extracts are not only potent inhibitors of serotonin release from platelets but also of polymorphonuclear leukocyte granules, providing a possible connection between the claimed benefit of feverfew in migraines and arthritis..... Feverfew appears to be an inhibitor of prostaglandin synthesis. Extracts of the above-ground portions of the plant suppress prostaglandin production; leaf extracts inhibit prostaglandin production to a lesser extent." .
Has anyone here tried Feverfew? Do you notice any similarities between it and other anti-serotonin drugs, like cyproheptadine or tianeptine?