I found a study that makes a compelling case for intermittent fasting:
Mice that were fed a high-fat diet developed obesity, hyperinsulinemia, hepatic steatosis, and inflammation.
Mice that were fed the same high-fat diet, but were restricted to an 8-hour feeding window, did not develop these symptoms. These mice ate the same total calories of the same high-fat food as the former group, yet remained lean and healthy.
The authors of the study attribute the benefits of the time-restricted feeding to a strengthening of metabolic/circadian rhythms. If nothing else, this study casts serious doubts on the "calories in, calories out" model of dieting and fat loss.
The full text is available here: http://www.sciencedirect.com/science/article/pii/S1550413112001891